Erapeutics. Mol. Cancer Ther. 15, 2475485 (2016). Li, A. M., Boichard, A. Kurzrock, R. Mutated TP53 is actually a marker of enhanced VEGF expression: evaluation of 7525 pan-cancer tissues. Cancer Biol. Ther. 21, 9500 (2020). Adashek, J. J., Goloubev, A., Kato, S. Kurzrock, R. Missing the target in cancer therapy. Nat. Cancer 2, 36971 (2021). Conroy, T. et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N. Engl. J. Med. 364, 1817825 (2011). Ang, C. et al. Clinical advantage from trametinib in a patient with appendiceal adenocarcinoma with a GNAS R201H mutation. Case Rep. Oncol. ten, 54852 (2017). Wilson, C. H., McIntyre, R. E., Arends, M. J. Adams, D. J. The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice by way of activation of Wnt and ERK1/2 MAPK pathways. Oncogene 29, 4567575 (2010). Ideno, N. et al. GNAS(R201C) induces pancreatic cystic neoplasms in mice that express activated KRAS by inhibiting YAP1 signaling. Gastroenterology 155, 1593607.e1512 (2018). Hattori, S. et al. Antibody against neurofibromatosis form 1 gene product reacts having a triton-insoluble GTPase activating protein toward ras p21. Biochem. Biophys. Res. Commun. 177, 839 (1991).five.6.7.eight.9.ten. 11. 12.13.14.15.16. 17. 18. 19. 20. 21. 22. 23.24.CODE AVAILABILITYStatistical analyses had been performed with SPSS version 25 application (IBM Corporation, Armonk, NY).25.26.Received: 22 August 2022; Accepted: 7 December 2022;27. 28.
biologyArticleBiological Extraction, HPLC Quantification and Health-related Applications of Astaxanthin Extracted from Crawfish “Procambarus clarkii” Exoskeleton By-ProductSalwa Hamdi 1, , Nour Elsayed two , Mohamed Algayar two , Verina Ishak two , Mariam Ahmed 2 , Sara Ahmed 2 , Mohamed Kamal two and Mohamed Abd El-Ghany 3, 1 2Zoology Division, Faculty of Science, Cairo University, Giza 12613, Egypt Biotechnology / Molecular Biochemistry Plan, Faculty of Science, Cairo University, Giza 12613, Egypt Botany and Microbiology Division, Faculty of Science, Cairo University, Giza 12613, Egypt Correspondence: [email protected] or salwa_abdelhamid@hotmail (S.H.); [email protected] or dr.mohamed.naguib@gmail (M.A.E.-G.); Tel.MCP-3/CCL7 Protein medchemexpress : +20-1093990866 (S.H.); +20-1116090451 (M.A.E.-G.)Citation: Hamdi, S.; Elsayed, N.; Algayar, M.; Ishak, V.; Ahmed, M.; Ahmed, S.; Kamal, M.; Abd El-Ghany, M.CD28 Protein Biological Activity Biological Extraction, HPLC Quantification and Healthcare Applications of Astaxanthin Extracted from Crawfish “Procambarus clarkii” Exoskeleton By-Product.PMID:24883330 Biology 2022, 11, 1215. doi.org/10.3390/ biology11081215 Academic Editors: Ramaraj Boopathy, Eldon R. Rene and Mark Zappi Received: 27 June 2022 Accepted: 9 August 2022 Published: 13 August 2022 Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.Very simple Summary: The study aims to provide an eco-friendly approach for the extraction on the natural pigment called “astaxanthin” from crawfish powder. Bacterial and fungal strains which might be advantageous to humans have been utilized as an alternative approach of extraction as opposed to using chemical substances. Astaxanthin concentration was determined working with an analytical tool referred to as “high-performance liquid chromatography” (HPLC). The results had been promising; however, future research can supply a lot more successful strategies for obtaining far better benefits. Several tests have been performed to evaluate the biological activity of extracted astaxanthin for instance antifungal, anti-inflammatory, antioxidant, as well as a.
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