September 2021

Thies.Introduction Prion diseases are uncommon fatal neurodegenerative ailments of humans and animals that are transmissible by exposure to diseased tissues via ingestion, injection or transplantation. These diseases are typically characterized…

N was PAD-mediated activation of a protein phosphatase 1-glycogen synthase kinase-3 (PP1-GSK3) signaling cascade . Our observation that AT8 pseudophosphorylation structurally exposes PAD aligns with prior structural research utilizing FRET…