Cynomolgus NKG2A&CD94 Protein 3286

Additional Information:
accession Q68VD2(NKG2A)&Q68VD4(CD94)|express systemHEK293|product tagC-His, C-Flag|purity> 95% as determined by Tris-Bis PAGE|backgroundThe ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.|molecular weightThe protein has a predicted MW of 17.01 kDa(NKG2A)&18.27 kDa(CD94). Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Cynomolgus NKG2A&CD94 Protein 3286proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceThe ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.Protein namesNKG2A proteinGene namesnkg2A,nkg2AMass26209DaSubellular locationMembrane ; Single-pass type II membrane protein .Target Relevance information above includes information from UniProt accession: Q68VD2The UniProt Consortium|