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Name :
CFD (Human) Recombinant Protein

Biological Activity :
Purified CFD (NP_001919.2 26 a.a. – 253 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.

Tag :

Protein Accession No. :
NP_001919.2

Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=1675

Amino Acid Sequence :
ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA

Molecular Weight :
28.16

Storage and Stability :
Store at -80°C. Aliquot to avoid repeated freezing and thawing.

Host :
Human

Interspecies Antigen Sequence :

Preparation Method :
Transfection of pSuper-CFD plasmid into HEK293H cell, and the expressed protein was purified by Strep-Tactin affinity column.

Purification :
Strep-Tactin affinity columns

Quality Control Testing :
SDS-PAGE and Western Blot SDS-PAGE Gel Western Blot

Storage Buffer :
100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.

Applications :
Western Blot, Enzyme-linked Immunoabsorbent Assay, SDS-PAGE, Protein Interaction,

Gene Name :
CFD

Gene Alias :
ADIPSIN, ADN, DF, PFD

Gene Description :
complement factor D (adipsin)

Gene Summary :
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq

Other Designations :
C3 convertase activator|D component of complement (adipsin)|complement factor D|complement factor D preproprotein|properdin factor D

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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